GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| BLCA | cis | rs9309473 | 1 | rs1403284 | chr2:73726662 | ALMS1P | chr2:73872046-73912692:+ | -0.31 | -4.49 | 9.38E-6 | Metabolite levels |
| BLCA | cis | rs2243480 | 1 | rs1404147 | chr7:65264524 | CCT6P1 | chr7:65216092-65228661:+ | 0.32 | 5.04 | 7.11E-7 | Diabetic kidney disease |
| BLCA | cis | rs1577917 | 1 | rs1415753 | chr6:86753074 | SNHG5 | chr6:86386726-86388451:- | -0.53 | -9.25 | 1.64E-18 | Response to antipsychotic treatment |
| BLCA | cis | rs853679 | 1 | rs1419183 | chr6:28242794 | ZNF389 | chr6:28129551-28137375:+ | -0.34 | -4.32 | 1.98E-5 | Depression |
| BLCA | cis | rs10461617 | 1 | rs1423620 | chr5:56100996 | C5orf35 | chr5:56205103-56213010:+ | 0.66 | 10.21 | 8.29E-22 | Type 2 diabetes |
| BLCA | cis | rs10461617 | 1 | rs1423621 | chr5:56101035 | C5orf35 | chr5:56205103-56213010:+ | 0.64 | 10.2 | 8.83E-22 | Type 2 diabetes |
| BLCA | cis | rs7714584 | 1 | rs1428551 | chr5:150259832 | LOC134466 | chr5:150310000-150326146:- | 0.44 | 5.81 | 1.31E-8 | Crohn's disease |
| BLCA | cis | rs7714584 | 1 | rs1428552 | chr5:150259831 | LOC134466 | chr5:150310000-150326146:- | 0.46 | 6.09 | 2.68E-9 | Crohn's disease |
| BLCA | cis | rs7714584 | 1 | rs1428554 | chr5:150257616 | LOC134466 | chr5:150310000-150326146:- | 0.48 | 6.25 | 1.09E-9 | Crohn's disease |
| BLCA | cis | rs7714584 | 1 | rs1428555 | chr5:150257391 | LOC134466 | chr5:150310000-150326146:- | -0.46 | -5.8 | 1.41E-8 | Crohn's disease |
| BLCA | cis | rs9475752 | 1 | rs1451707 | chr6:56801877 | BEND6 | chr6:56819773-56892138:+ | -0.3 | -4.11 | 4.92E-5 | Menarche (age at onset) |
| BLCA | cis | rs9475752 | 1 | rs1451708 | chr6:56802201 | BEND6 | chr6:56819773-56892138:+ | -0.3 | -4.11 | 4.92E-5 | Menarche (age at onset) |
| BLCA | cis | rs2905426 | 1 | rs1469712 | chr19:19528821 | YJEFN3 | chr19:19639720-19648393:+ | -0.23 | -4.44 | 1.16E-5 | Schizophrenia |
| BLCA | cis | rs4803468 | 1 | rs1473248 | chr19:41923314 | B3GNT8 | chr19:41931265-41934635:- | 0.21 | 4.03 | 6.61E-5 | Height |
| BLCA | cis | rs1474698 | 1 | rs1474698 | chr6:56064197 | COL21A1 | chr6:55921389-56258892:- | -0.33 | -6.12 | 2.34E-9 | Pulse pressure |